The global Niemann Pick C Like protein market is anticipated to grow at a significant CAGR during the forecast period. Niemann-Pick C1-Like 1 (NPC1L1) is a polytopic transmembrane protein localized at the apical membrane of enterocytes and the canalicular membrane of hepatocytes. It acts as a sterol transporter to reconcile intestinal cholesterol absorption and counter-balances hepatobiliary cholesterol excretion. Generally found on the gastrointestinal tract epithelial cells as well as in hepatocytes, it appears to bind to a critical mediator of cholesterol assimilation. When the human body fails to transport cholesterol and other fatty substances (lipids) inside of cells, it results in a medical condition (a rare progressive genetic disorder known) as Niemann-Pick disease type C. This leads to the abnormal accumulation of these substances within various tissues of the body, primarily the brain tissue. The accumulation of these substances damages the affected areas. Thus, in order to resolve the therapeutic challenges related to the disease, the global Niemann Pick C Like protein market is anticipated to grow in the future years.
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Niemann-Pick disease type C is highly volatile, resultantly, the age of developing the disease and its specific symptoms also vary from person to person. Niemann-Pick disease type C can range from a fatal disorder within the first few months after birth (neonatal period) to a late development (chronic progressive disorder that remains undiagnosed into adulthood). Most cases are detected during childhood and progress to cause life-threatening complications by the second or third decade of life. Niemann Pick C1 Like Protein 1 pipeline target has so far constituted close to 8 molecules.
Market Coverage
- The market number available for – 2020-2027
- Base year- 2020
- Forecast period- 2021-2027
- Segment Covered-
o By Application
o By Deployment Model
- Regions covered-
o North America
o Europe
o Asia-Pacific
o Rest of the World
- Competitive Landscape: Merck & Co., Inc., and Esperion Therapeutics, Inc., among others.
Key questions addressed by the report
- What is the market growth rate?
- Which segment and region dominate the market in the base year?
- Which segment and region will project the fastest growth in the market?
- How COVID-19 impacted the market?
o Deviation from the pre-COVID-19 forecast
o Most affected region and segment
- Who is the leader in the market?
- How are players addressing challenges to sustain growth?
- Where is the investment opportunity?
Global Niemann Pick C1 Like Protein 1 Market Report by Segment
By Type
- KT-6971
- HS-25
- Bempedoic Acid
- Ezetimibe
- Others
By Application
- Hospital
- Clinic
- Others
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Niemann Pick C1 Like Protein 1 Market– Segment by Region
North America
- United States
- Canada
Europe
- Germany
- United Kingdom
- France
- Spain
- Italy
- Rest of Europe
Asia-Pacific
- China
- Japan
- India
- Rest of Asia-Pacific
Rest of the World
- Middle East & Africa
- Latin America
Company Profiles
- Merck & Co., Inc.
- Esperion Therapeutics, Inc.
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