The global monoclonal antibodies market is estimated to grow at a CAGR of 8.6% during the forecast period. The increasing prevalence of cancer and auto-immune diseases and increasing research on monoclonal antibodies are some crucial factors accelerating market growth. There are more than 80 autoimmune diseases and some of them are well known, including multiple sclerosis, type 1 diabetes, rheumatoid arthritis, and lupus, while others are difficult and rare to diagnose. National Institutes of Health (NIH) estimates that auto-immune diseases affect over 24 million people in the US and a further eight million people have autoantibodies, blood molecules which show an individual’s possibility of developing an autoimmune disease.
Type 1 diabetes is a kind of autoimmune disease. In type 1 diabetes, the immune system attacks and destroys the cells that produce insulin, and thereby, the pancreas are not able to produce insulin. As per the International Diabetes Federation (IDF), nearly 10% of all people suffering from diabetes have type 1 diabetes. Anti-CD3 monoclonal antibodies are a novel class of drugs that are indicated to support preserve function of beta-cell if used early in the onset of type 1 diabetes mellitus. Preserving beta-cell function might delay the requirement for exogenous insulin treatment, which in turn, minimizes the risks of low blood sugar (hypoglycemic) events that are associated with insulin treatment.
Some monoclonal antibodies for type-1 diabetes are in clinical phases. For instance, in May 2019, GeNeuro declared positive phase IIa trial outcomes for temelimab. It is a monoclonal antibody targeting protein involved in the inception and development of type 1 diabetes, which makes the drug an effective disease-modifying therapy for type-1 diabetes. A 30% decrease in hypoglycemic events has been reported by research among adults suffering from type 1 diabetes treated with temelimab. Such kinds of monoclonal antibody therapies are expected to deliver hope for patients with type-1 diabetes to reduce the possibility of hypoglycemia.
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Scope of the Global Monoclonal Antibodies Market
Market Coverage
- Market number available for 2021-2029
- Base year- 2021
- Forecast period- 2023-2029
- Segment Covered- By Source and Application
- Regions Covered- North America, Europe, Asia-Pacific, and Rest of the World
- Competitive Landscape- Amgen Inc., Eli Lilly & Co., F- Hoffman La-Roche AG, Pfizer Inc., and Novartis AG
Monoclonal Antibodies Market-Segmentation
By Source
- Murine
- Chimeric
- Human
- Humanized
By Application
- Cancer
- Infectious Diseases
- Auto-Immune Diseases
- Inflammatory Diseases
- Others
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Monoclonal Antibodies Market– Segment by Region
North America
- United States
- Canada
Europe
- UK
- Germany
- Spain
- France
- Italy
- Rest of Europe
Asia-Pacific
- India
- China
- Japan
- South Korea
- Rest of APAC
Rest of the World
- Middle East & Africa
- Latin America
Company Profiles
- AbbVie, Inc.
- Amgen, Inc.
- AstraZeneca plc
- Aytu BioScience, Inc.
- Bayer AG
- Biocon, Ltd.
- Biogen, Inc.
- Bristol Myers Squibb Co.
- Cadila Pharmaceuticals, Ltd.
- Daiichi Sankyo Company, Ltd.
- Reddy’s Laboratories, Inc.
- Eli Lilly and Co.
- Hoffmann-La Roche AG
- Genmab A/S
- Gilead Sciences, Inc.
- GlaxoSmithKline plc
- Innate Pharma S.A.
- ntas Biopharmaceuticals, Ltd.
- Johnson & Johnson Services, Inc.
- Lupin, Ltd.
- Merck & Co., Inc.
- Mylan N.V.
- Novartis AG
- Oncologie, Inc.
- Orchard Therapeutics plc
- Pfizer, Inc.
- Sanofi S.A.
- Spectrum Pharmaceuticals, Inc.
- Sun Pharmaceutical Industries, Ltd.
- Takeda Pharmaceutical Co., Ltd.
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