The hdac histone deacetylase inhibitor market is anticipated to grow at a significant CAGR of 7.4% during the forecast period (2022-2028). Hdac histone deacetylase inhibitor is used in the treatment of cancer. Hdac histone deacetylase inhibitors are involved in biological processes which promote the development and proliferation of the death of cells which are in the body. They are a new form of anti-cancer drugs which are responsible for epigenetic or nonepigenetic regulation. This regulates cell cycle arrest in the body where cancer cells are present. Hdac histone deacetylase inhibitor does chromatin remodeling which is a type of epigenetic regulation. The acetylation process which is done on histones by histone deacetylase inhibitor changes their form and induces their charge from positive to negative. With this change, there are fewer chances of their interaction with negatively charged DNA. Transcriptional activation happens with an increase in accessibility of transcriptional machinery. Histone deacetylase causes epigenetic changes as there is an imbalance between histone deacetylase and histone acetyl-transferases. P53 and RUNX3 are some of the tumor suppressors which are not likely to work in many types of cancers due to aberrant epigenetic changes. Factors such as significant investment in cancer R&D activities, rising number of collaborations and investment by companies in histone deacetylase inhibitor manufacturing driving the market growth.
The global Hdac histone deacetylase inhibitor market is segmented by type and by disease. Based on type, the market is sub-segmented into Class 1, Class 2, Class 3, and Class 4. Based on disease, the market is sub-segmented into cancer and others. Cancer is a disease in the human body in which there is an uncontrollable growth of the cells in the body and these cells spread to other parts of the body. As per the American cancer society, around 1,898,160 new cancer cases and 608,570 cancer deaths occurred in the united states in the year 2021.
Some major players in the market include Merck & Co., Inc., Novartis AG, Spectrum Pharmaceuticals, Inc., Pfizer Inc. The market players are contributing significantly to the growth of the market by the adoption of various strategies including mergers & acquisitions, geographical expansion, partnerships and collaborations, and new product launches, to stay competitive in the market. For instance, in March 2021, OnKure, Inc. is a biopharmaceutical company that develops oncology therapeutics have announced that it had raised $55 million in Series B financing. According to the company, this financing will be used in the development and advancement of histone deacetylase (HDAC). Acorn Bioventures was behind this financing with some more investors such as Cormorant Asset Management, Surveyor Capital.
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Market Coverage
- The market number available for – 2021-2028
- Base year- 2021
- Forecast period- 2022-2028
- Segment Covered-
- By Type
- By Disease
- Regions Covered-
- North America
- Europe
- Asia-Pacific
- Rest of the World
- Competitive Landscape- Merck & Co., Inc., Novartis AG, Spectrum Pharmaceuticals, Inc., Pfizer Inc., and others.
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Hdac Histone Deacetylase Inhibitor Market Report By Segment
By Type
- Class 1
- Class 2
- Class 3
- Class 4
By Disease
- Oncology
- Neurology
- Others
Key questions addressed by the report
- What is the market growth rate?
- Which segment and region dominate the market in the base year?
- Which segment and region will project the fastest growth in the market?
- How has COVID-19 impacted the market?
- Deviation from the pre-COVID-19 forecast
- Most affected region and segment
- Who is the leader in the market?
- How players are addressing challenges to sustain growth?
- Where is the investment opportunity?
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